João Guilherme

Internacional

João Guilherme started his career with Brazilian powerhouse Internacional where he played 16 games, and scored 1 goal.

Marítimo

In January 2008, Guilherme was officially announced as the first reinforcement of the year of Portuguese Liga club C.S. Marítimo, after completing a deal worth €200,000. He was signed along with Internacional teammate Bruno Grassi, both of whom joined up with former teammates Marcelo Boeck, Ediglê and Márcio Mossoró, who all signed for Marítimo earlier in the season from Internacional. He played for Maritimo from 2008 until 2013, appearing in 109 games and scoring 5 goals.

APOEL

On 14 June 2013, after six Portuguese Liga seasons, he signed a two-year contract with APOEL from Cyprus. He made his APOEL debut against NK Maribor at GSP Stadium on 31 July 2013, in a 1–1 first leg draw for the third qualifying round of the 2013–14 UEFA Champions League. He scored his first official goal for APOEL on 2 September 2013, in his team's 3–0 home win against Enosis Neon Paralimni for the Cypriot First Division. During the 2013–14 season, he appeared in four 2013–14 UEFA Europa League group stage matches for APOEL and won all the titles in Cyprus, the Cypriot League, the Cypriot Cup and the Cypriot Super Cup. The next season, he appeared in five group stage matches in APOEL's 2014–15 UEFA Champions League campaign. On 19 December 2014, Guilherme signed a two-year contract extension with APOEL, running until June 2017. On…

João Guilherme was the captain of the Brazil under-17 team that won the 2003 FIFA U-17 World Cup, appearing in all Brazil's matches and helping his team to win the trophy.

As of 15 May 2016

APOEL Cypriot First Division: 2013–14, 2014–15, 2015–16 Cypriot Cup: 2013–14, 2014–15 Cypriot Super Cup: 2013 Brazil U17 FIFA Under-17 World Cup: 2003