Santi Comesaña

Coruxo

Born in Vigo, Galicia, Comesaña was an ED Val Miñor youth graduate. On 9 July 2015, he signed for Segunda División B side Coruxo FC, after impressing on a trial basis. On 22 August 2015, Comesaña made his senior debut, starting and scoring his team's second in a 3–2 away win against Atlético Astorga FC. On 6 December, he scored a hat-trick in a 5–1 home routing of SD Compostela.

Rayo Vallecano

On 16 July 2016, after scoring eight goals in 37 matches during the campaign, Comesaña signed a four-year contract with Rayo Vallecano, freshly relegated to Segunda División. He made his professional debut on 28 August, coming on as a second-half substitute for Adri Embarba in a 0–0 home draw against Real Valladolid. Comesaña scored his first professional goal on 1 April 2017, netting the first in a 3–1 away win against Girona FC. He renewed his contract until 2023 on 17 October, contributed with two goals in 33 appearances during the 2017–18 campaign, as his side achieved promotion to La Liga as champions. Comesaña made his debut in the main category of Spanish football on 25 August 2018, starting in a 1–0 away loss against Atlético Madrid. He scored his first goal in the category on 20 January 2019, netting the opener in a 2–2 home draw against Real Sociedad.

Villarreal

On 29 June 2023, Comesaña signed a four-year contract with Villarreal CF also in the top tier.

Club

As of match played 17 May 2026

Rayo Vallecano

Segunda División: 2017–18