Franco Calderón

Calderón's senior career began with Unión Santa Fe. He previously had youth stints with Charata Juniors and Cooperativista. Leonardo Madelón moved the defender into the first-team set-up in 2018–19, subsequently selecting Calderón to start a Copa de la Superliga first round, first leg at the Estadio La Ciudadela on 13 April 2019; he appeared for the full duration of a 1–1 draw. By the conclusion of 2019–20, Calderón had made thirteen appearances in all competitions for Unión; a period in which he scored his first goal, netting in a Copa Argentina first round defeat to Primera C Metropolitana's Dock Sud. In 2024, Calderón moved to Chile and joined Universidad de Chile. In August 2026, he was loaned out to Independiente on a deal until December 2027 with a purchase option for the 80% of his rights.

As of 28 August 2020.

Calderón's twin brother, Pablo, is also a professional footballer.