Akis Zikos

He won 18 caps for Greece, but fell out of favor when coach Otto Rehhagel took over the team. After helping Monaco to the 2004 UEFA Champions League Final, he was considered for selection in Greece's victorious Euro 2004 squad, however he was ultimately overlooked.

Skoda Xanthi

Zikos started his professional career in 1993 with Skoda Xanthi for whom he spent 4 seasons in the Alpha Ethniki.

AEK Athens

In the summer of 1998 Zikos was transferred to AEK Athens for a fee of 130 million drachmas. He immediately established himself as the team's main defensive midfielder and it didn't take him long to impress with his performances. He was a key player with all the coaches who passed through the team's bench, while he gradually played more and more in the national team. With the transfer of Thodoris Zagorakis to the club in 2000, they formed an amazing partnership in the midfield of the team for two years. Zikos won the Greek Cup in two occasions, 2000 and 2002. In the summer of 2002, not having the best relations with the then administrative leader of the team, Psomiadis, he decided to leave, taking the big step abroad at the same time.

Monaco

In the summer of 2002 he was signed by Monaco, where he played for four seasons in Ligue 1. He also proved his talent with the club on the European stage. In 2003, he won the Coupe de la Ligue and in 2004, under Didier Deschamps they made it to the UEFA Champions League Final where they lost to José Mourinho's Porto in Arena AufSchalke, Gelsenkirchen. Despite their heavy loss (3–0 for FC Porto), Zikos was recognized one of the best players on the pitch that day. His appearance in the final made Zikos the first Greek to play in a UEFA Champions League final.

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AEK Athens

Greek Cup: 1999–2000, 2001–02 Monaco

French League Cup: 2003 UEFA Champions League: Runner-up 2003–04