Aldo de Nigris

De Nigris started his career at the youth divisions of Tigres UANL, the biggest rival of CF Monterrey. Tigres debuted him in Liga MX. He played some irregular seasons with Tigres, Veracruz and Necaxa until he arrived at Monterrey. In the first game after his brother's death, he dedicated his only goal to him in an Apertura 2009 playoff game against América on 21 November 2009 in the second minute of the second half. He then scored two goals against Toluca in the semi-final. He also scored in the final against Cruz Azul, giving Monterrey the lead, and eventually dedicating the winning championship to his late brother. A year later, de Nigris won his second league title with Monterrey, this time against Santos Laguna. On 27 April 2011, Monterrey won the CONCACAF Champions League, where they defeated MLS club Real Salt Lake in the final. De Nigris was their top goal scorer, with four, tied with teammate Humberto Suazo

C.D. Guadalajara

On 1 July 2013, de Nigris signed with C.D. Guadalajara for 5 million dollars until 30 June 2016. He made his debut with the club on 18 August 2013 in a home match against Puebla F.C.

Return to C.F. Monterrey 2015

On 10 June 2015, de Nigris returned to Rayados. Yet the exact amount of the transaction is not known. He retired in 2017.

De Nigris was called up to the Mexico national football team for the friendly matches against Bolivia on 24 February 2010 and New Zealand on 3 March 2010. Mexico defeated Bolivia 5–0, in which de Nigris entered the game as a substitute. He started in his first game for Mexico against New Zealand, in which he played the first forty-five minutes, until being taken off at half-time. Mexico would win 2–0. He was left out of Javier Aguirre's 23-man squad for the 2010 FIFA World Cup due to an ankle injury, in which he took 12 weeks to recover. On 29 March 2011, he scored his first international goal in a friendly match against Venezuela.

2011 CONCACAF Gold Cup

De Nigris was named in the 23-man squad to participate in the CONCACAF Gold Cup. On 5 June he scored the second goal in the 5–0 over El Salvador after coming on as a substitute in the second-half. On 9 June de Nigris again scored after coming off the bench in a 5–0 win over Cuba. Three days later, he would score again coming on in the second half in the quarter-final match against Guatemala. After Mexico and Honduras held each other to a 0–0 draw in the semi-final match, de Nigris opened the score in the first half of extra-time, heading in a corner kick. Mexico would win the match 2–0, thus advancing to the final.

International

Scores and results list Mexico's goal tally first, score column indicates score after each de Nigris goal.

Aldo is the youngest of three brothers. They grew up on the south side of Monterrey. His oldest brother, "Poncho" de Nigris, is a TV host and influencer. His other brother, the late Antonio "Toño" de Nigris, was also a footballer who played for CF Monterrey and the Mexico national team as well. On 15 November 2009, Antonio died from a heart attack at the age of 31 in Greece while playing for AEL. His family is Italian on his father's side.