Facundo Medina

Medina's career got underway with a stint with River Plate, for which he was an unused substitute four times during the 2016–17 Argentine Primera División season. In January 2018, Medina completed a move to fellow Argentine Primera División side Talleres. After featuring for their U20s at the 2018 U-20 Copa Libertadores in February, he made his first league appearances in August when he played in matches against Boca Juniors, Rosario Central and Gimnasia y Esgrima. He scored his first senior goal in February 2020 against Huracán.

Lens

After a total of 37 appearances for Talleres, Medina departed in July 2020 to join Ligue 1 side Lens. Medina netted his first goal for Lens on 13 September against Lorient, scoring with an overhead kick as his side won 3–2 away from home. He scored again on 3 February 2021 during a 2–2 draw at home to Marseille. His third Lens goal arrived on his Coupe de France starting debut in a defeat away to Championnat National club Red Star on 6 March. On 18 January 2023, he extended his contract with Lens until 2026.

Marseille

On 2 July 2025, Medina signed for fellow Ligue 1 club Marseille on loan for the remainder of the 2025–26 season with an option to buy if agreed upon. By the conclusion of the 2025–26 season, he joined the club permanently for a transfer fee of €18m.

Bayer Leverkusen

On 11 August 2026, Medina signed a five-year contract with Bayer Leverkusen. The transfer fee was reportedly €25m including add-ons.

After playing in all three of Talleres' fixtures at the beginning of 2018–19, Medina received a call-up to the Argentina U20 squad. He subsequently featured on 29 August 2018 in a friendly with Uruguay. He had previous experience with the U20s during his time with River Plate, and was also called up to train against the senior squad during the 2018 FIFA World Cup in Russia. In December, Medina was selected for the 2019 South American U-20 Championship. He was also picked for the subsequent FIFA U-20 World Cup. He featured eleven times in the tournaments. Medina was called by the U23s for the 2019 Pan American Games. Medina appeared in all five of Argentina's matches at the Pan American Games, as they came away with the trophy after defeating Honduras in the final. In September 2020, having won the 2020 CONMEBOL Pre-Olympic Tournament with the U23s months earlier, Medina received his first call-up to the Argentina senior squad from manager Lionel Scaloni. He debuted in a 2022 FIFA World Cup qualifying victory away to Bolivia on 13 October, after replacing Lautaro Martínez for the final moments at the Estadio Hernando Siles. On 27 May 2026, Medina was selected in the 26-man squad for the 2026 FIFA World Cup.

Club

As of match played 29 August 2026

International

As of match played 19 July 2026

Argentina U23

Pan American Games: 2019 CONMEBOL Pre-Olympic Tournament: 2020 Argentina

FIFA World Cup runner-up: 2026