Gianluca Mancini

Perugia

Mancini left for Perugia on loan in mid–2015, with an option to purchase. Mancini made his professional debut in the Serie B for Perugia on 11 September 2015 in a game against Pescara. After a brief return to Florence, by the club excising the counter-option. on 1 August 2016, Fiorentina announced that they had sold Mancini to Perugia outright for free. It was later revealed that Fiorentina was eligible to 50% future transfer fee.

Atalanta

In January 2017, Mancini and Alessandro Santopadre, son of Massimiliano Santopadre, chairman of Perugia, were signed by Atalanta for €200,000 and €1 million transfer fees respectively. They were immediately loaned back to Perugia from Atalanta. The deal was later accused by the prosecutor as a manipulation of transfer fees, which overstated the price-tag of Santopadre and understated Mancini. The chairman and both clubs were acquitted of any wrongdoing in July 2018. Mancini made his Serie A debut in a 1–1 draw against his former team Fiorentina, replacing Rafael Toloi after 25 minutes. On 4 February 2018, he scored his first goal in a 1–0 for Atalanta against Chievo in Serie A.

Roma

On 17 July 2019, Mancini joined Roma on loan with a conditional obligation to buy for €13 million plus bonuses and a 10% sell on fee. Mancini scored an own goal in the 2023 Europa League final against Sevilla, which Sevilla ultimately won on penalties. This made him the first player to score in a European final against a team…

On 1 September 2017, Mancini made his international debut with the Italy U21 team in a 3–0 friendly loss against Spain. On 15 March 2019, Gianluca Mancini received a call-up from Roberto Mancini for Italy's UEFA Euro 2020 qualifying matches against Finland and Liechtenstein. On 26 March, he made his senior international debut in a 6–0 home win over Liechtenstein. He took part in the 2019 UEFA European Under-21 Championship.

Mancini is a tall and physically strong central defender capable of playing in both a three or a four-man defensive line. Among his strengths are his excellent heading ability, which makes him a likely goal threat in the opposition's penalty box. Besides his regular position, he can also play as a right–sided full-back and a defensive-midfielder, mainly out of necessity. He has cited Marco Materazzi as his favourite defender of all time.

In December 2019, Gianluca married his long-term partner, Elisa; together they have two daughters. Despite sharing a surname, he is not related to Italian football manager Roberto Mancini.