Jailson

Chapecoense

Jailson made his professional debut on 18 March 2015, playing for Chapecoense in a Copa do Brasil match against Interporto, entering the field in the second half of a 5–2 away victory.

Grêmio

In January 2016, Jailson returned to his parent club Grêmio. He made his debut for the club in a 3–2 away loss against São Paulo-RS for the Campeonato Gaúcho. Jailson scored his first professional goal in a 3–3 away draw against former club Chapecoense for the Campeonato Brasileiro.

Fenerbahçe

On 30 August 2018, Jailson joined Süper Lig club Fenerbahçe S.K.

Dalian Pro

On 18 September 2020, Jailson signed with Chinese Super League (CSL) club Dalian Pro. He did not play for the team in 2021 as he was unable to return to China.

Palmeiras

On 7 January 2022, Jailson signed with Palmeiras.

Celta

On 28 December 2023, Jailson moved to Spain, signing a contract until 30 June 2025 with La Liga club Celta de Vigo.

Los Angeles FC

On 2 September 2025, MLS club Los Angeles FC signed free agent midfielder Jailson through the remainder of the 2025 season with club options for 2026 and 2027. At the end of the season, Jailson's contract option was declined.

As of match played 2 November 2025

Grêmio

Copa do Brasil: 2016 Copa Libertadores: 2017 Recopa Sudamericana: 2018 Campeonato Gaúcho: 2018 FIFA Club World Cup runner-up: 2017 Palmeiras

Recopa Sudamericana: 2022 Campeonato Paulista: 2022, 2023 Série A: 2022, 2023 Supercopa do Brasil: 2023 FIFA Club World Cup runner-up: 2021