Jeffinho

Resende

Jeffinho began his career at Resende after playing youth football for Pelé Academia, which had a partnership with the club. He made his first team debut on 28 June 2020, coming on as a second-half substitute and scoring his team's second in a 2–0 Campeonato Carioca away win over Madureira. Jeffinho continued to feature sparingly for Resende before moving to Gama on loan for the 2021 Série D. Back to his parent club, he impressed during the 2022 Carioca.

Botafogo

On 12 April 2022, Jeffinho moved to Botafogo on loan; initially assigned to the B-team, Jeffinho was called up to the first team squad of Bota by manager Luís Castro in June 2022. He made his main squad – and Série A – debut on 19 June, replacing Renzo Saravia late into a 3–2 away success over Internacional. On 26 August 2022, Jeffinho signed a permanent three-year contract with Bota.

Lyon

On 31 January 2023, Jeffinho joined Ligue 1 club Lyon for a fee of €10 million, signing a contract until June 2027 with the French club. On 28 February 2023, for his first start with Lyon, he scored his first goal, during a quarter-final of the Coupe de France against Grenoble. On 3 June 2023, Jeffinho scored his first Ligue 1 goal in a game against Nice.

Return to Botafogo

On 5 January 2024, Lyon sent Jeffinho back to Botafogo on loan until the end of 2024. On 31 December 2024, his move to Botafogo was made permanent for a reported transfer fee of €5.3 million.

Loan to China…

As of match played 31 May 2026

Botafogo

Série A: 2024 Copa Libertadores: 2024 Taça Rio: 2024