Milton Casco

Born in María Grande, Entre Ríos Province, Casco began his professional career with Gimnasia y Esgrima La Plata of the Argentine Primera División in 2009. In July 2012 he signed for Newell's Old Boys under manager Gerardo Martino, who bought 50% of his economic rights. In August 2015, Casco was close to a €2.5 million move to French club Olympique de Marseille. The transfer fell through when compatriot Marcelo Bielsa unexpectedly resigned as the Ligue 1 team's manager. On 9 September 2015, Casco signed a three-year contract with CA River Plate, with the Buenos Aires–based club purchasing 85% of his economic rights for $3 million. He made his debut four days later in the Superclásico against arch-rivals Boca Juniors, a 1–0 home loss. On 18 July 2017 he signed an extension until June 2020. On 12 February 2021 he signed an extension until December 2023. On 13 September 2022, he extended his contract until December 2025. On 6 January 2026, Casco signed with Atlético Nacional.

On 27 May, uncapped Casco was selected by coach Gerardo Martino for the 2015 Copa América in Chile. He made his debut in a preparation friendly on 7 June at the Estadio San Juan del Bicentenario, filling in for Facundo Roncaglia for the final 29 minutes of a 5–0 win over Bolivia; however, he did not feature in the tournament, in which his country lost to the hosts in the final. Absent from the national team since the 2015 tournament, Casco was a surprise inclusion for the 2019 Copa América in Brazil, with Lionel Scaloni picking him ahead of Gabriel Mercado. He played one game of a third-place finish, the 1–1 group draw with Paraguay at the Mineirão.

Newell's Old Boys

Argentine Primera División: 2013 Final River Plate

Recopa Sudamericana: 2016, 2019 Copa Argentina: 2015–2016, 2016–2017, 2019 Supercopa Argentina: 2017, 2019 Copa Libertadores: 2018 Argentine Primera División: 2021, 2023 Trofeo de Campeones: 2021, 2023 Argentina

Copa América: runner-up 2015, third place 2019