Santiago Mouriño

Racing Montevideo

Mouriño played with Nacional as a youngster but left the club in 2021 without signing a professional contract, although they maintained a percentage of his ownership. He joined Racing Montevideo in January 2022 and made his professional debut on 22 May 2022 as a second half substitute in a 2–0 win against Progreso. Mouriño would go on to play fifteen league games in 2022 as Racing returned to the top flight of Uruguayan football after being crowned champions of the 2022 Segunda División. He made his Primera División debut on 4 February 2023, starting in a 2–0 loss against Boston River.

Atlético Madrid

On 6 July 2023, Mouriño signed a five-year contract with La Liga side Atlético Madrid.

Loan to Zaragoza

On 11 August 2023, Mouriño joined Segunda División club Real Zaragoza on a season long loan deal.

Alavés

On 27 August 2024, Mouriño signed a five-year contract with Spanish top tier club Deportivo Alavés.

Villarreal

On 1 August 2025, Atlético Madrid exercised the buy-back option in Mouriño's contract. He was sold to Villarreal on the same day, where he signed a five-year contract.

In June 2023, Mouriño received his first call-up to the Uruguay national team for friendly matches against Nicaragua and Cuba. He made his debut on 10 October 2025 in a 1–0 friendly win against the Dominican Republic.

Club

As of match played 20 September 2026

International

As of match played 10 October 2025

Racing Montevideo

Uruguayan Segunda División: 2022 Individual

La Liga Team of the Season: 2025–26