Anthony Domingo Silva

Silva began his career in the youth ranks of Club Cerro Corá. In 2000, he made his professional debut with the club.

Libertad

Silva was signed by Club Libertad in 2003. During the 2004 Copa Libertadores, Silva helped Libertad to a famous 1–0 win over Argentine club River Plate in a match played at Defensores del Chaco on 7 April. Argentina's Clarín raved about Silva's performance, stating: "The goalkeeper Anthony Silva was the big star: he closed off all roads to the Argentines."

Loan to General Caballero ZC

After being primarily the reserve goalkeeper for Libertad, Silva joined General Caballero on loan during the 2005 season. Silva's rights were purchased by Italian club Genoa but never officially joined the Italian side.

Loan to 2 de Mayo

In 2006 Silva signed on loan with Club 2 de Mayo and established himself as the teams' main goalkeeper. During Silva's loan to 2 de Mayo, he was coached by Saturnino Arua and was teammates with Salustiano Candia. On 15 March 2006, gave apologies for making improper gestures at the public after being replaced after conceding his side's fourth goal in a defeat to Nacional Asunción, showing his middle finger to the preference section at the Estadio Defensores del Chaco.

"They are things that occur. I reacted in that moment because I was angry and what I did was a matter of in the moment, because I don't have a past with actions of this type. Also, I don't know to who I showed it to, and the only thing that…

Silva has represented Paraguay at various youth levels. In 2001 Silva participated for Paraguay in the Under-17 World Cup and in 2003 participated in the Under-20 World Cup helping his nation reach the knock out stages. He played 3 matches in the 2003 Pan American Games. He was part of the squad that played in the 2015 Copa América, where he played 2 matches. He also was selected for the squad that competed in the Copa América Centenario. In the 2021 Copa América, Paraguay's press hailed Silva as the figure for his saves during a quarter-final penalty shootout against Peru, which Paraguay ultimately lost. Silva saved penalties from Santiago Ormeño and Christian Cueva before Paraguay lost 4–3 in the shoot-out.

Club

This table is incomplete, thus some stats and totals could be incorrect.

International

Club Libertad

Primera División: 2003, 2006 Deportes Tolima

Categoría Primera A runner-up: 2010 Finalización Independiente Medellín

Categoría Primera A runner-up: 2015 Apertura