Jaime Lozano

Lozano made his professional debut with Universidad Nacional in 1998. After a brief stint with Celaya, he went back to his former club, where, under the leadership of Hugo Sánchez, he won two consecutive league titles in 2004. In the years that followed, Lozano played for Tigres UANL, Cruz Azul and Morelia, before making his return to Universidad Nacional, where he concluded a 15-year career.

Lozano was capped 34 times for the Mexico national team; he made three appearances in the team's fourth-place finish at the 2005 FIFA Confederations Cup, and eleven in the 2006 FIFA World Cup qualifiers. A series of injuries kept him away from the team in the months leading up to the World Cup. Nevertheless, Lozano was named by Ricardo La Volpe in a provisional list of 26 players. However, he did not make the final list. Lozano was one of the players selected by Hugo Sánchez to compete in the Copa América 2007. He made his first appearance in the tournament coming on as a substitute in Mexico's opening 2–0 group stage victory over Brazil.

Querétaro

After winning the U-20 Clausura Liga MX title with Querétaro FC's U-20 team, Lozano was promoted to be an assistant coach at Querétaro's senior team under Víctor Manuel Vucetich. After Vucetich was sacked on 31 January 2017, Lozano was appointed manager. On 16 July, he won his first career title as a manager when Querétaro defeated América 2–0 to clinch the 2017 Supercopa MX. On 22 October, Lozano was sacked after a poor run of form which left Querétaro in last place, being replaced by Luis Fernando Tena.

Mexico U23

On 18 December 2018, Lozano was named manager of the Mexico U-23 national team. At the 2019 Toulon Tournament, Lozano took the team to a third-place finish, defeating the Republic of Ireland in a penalty shoot-out 4–3 following a scoreless draw. Disputing the Pan American Games the following month, he led the team to a third-place finish, defeating Uruguay 1–0, receiving the bronze medal. At the 2020 Summer Olympics, Lozano took the U-23 team to a third-place finish, defeating hosts Japan 3–1 in the bronze medal match.

Necaxa

On 9 February 2022, Lozano was appointed as manager of Liga MX side Necaxa. He led the team to the Reclassification phase of the Clausura 2022, where they tied 1–1 on aggregate but lost 3–1 in a penalty shoot-out to Cruz Azul. After Necaxa failed to get past the Reclassification phase in the Apertura 2022 following a 2–0 defeat to Tigres UANL, Necaxa and Lozano mutually parted ways.

Mexico national…

Lozano's parents were both telenovela actors, and was given the nickname "El Actor" during his playing career. His mother is actress Ana Bertha Espín and his father is actor of the same name Jaime Lozano. During the peak of his career, Lozano was featured on the North American cover of EA Sports' 2006 FIFA World Cup video game alongside Claudio Reyna. He did not make Mexico's final roster that participated at the World Cup.