Mahmood Khan

Afghan Chaman

Khan made his Pakistan Premier League debut for Afghan Chaman in the 2008–09 season.

Loan to Karachi Port Trust

Khan had a brief stint at departmental side Karachi Port Trust in 2009.

Khan Research Laboratories

In 2009, Khan signed for departmental side Khan Research Laboratories (KRL), along with teammate Kaleemullah Khan. With KRL, he won three consecutive league titles, in 2011–12, 2012–13 and 2013–14, as well as three national cups, in 2012, 2015 and 2016. He also participated in the AFC President's Cup from 2012 to 2014. He was a member of the team which reached the 2013 AFC President's Cup final, after falling 0–1 to Turkmen club Balkan FT in the final. On 10 May 2013, Khan scored a memorable Olympic goal from a corner kick in the 12th minute, in the group stage of the 2013 President Cup against Philippines club Global FC, which ended in a 2–0 victory for Khan's side.

Loan to Karachi Port Trust

Khan was again loaned briefly to Karachi Port Trust in 2011.

K-Electric

Khan signed for K-Electric in January 2016, along with his brother Dawood Khan.

Sui Southern Gas

Khan signed for SSGC FC in the 2018–19 season following the restoration of the Pakistan Premier League after three years since 2015. In 2021, SSGC club was closed after the shutdown of departmental sports in Pakistan. After the restoration of departmental sports in Pakistan, SSGC terminated contracts of the players of the squad on 26…

Khan represented the Pakistan under-23 team at the 2010 Asian Games and in a two-match friendly series against Palestine in 2011. Khan got his first senior team cap at the 2012 AFC Challenge Cup qualification. After several friendlies in 2013 and 2014 with the senior team, Khan represented Pakistan at the 2014 Asian Games as part of national U-23 team against China U-23 on 22 September 2014, in a 1–0 loss. In February 2015, Khan played in a friendly against Afghanistan, ending in a 2-1 victory for Pakistan. He was subsequently called in the 2018 FIFA World Cup qualification against Yemen. Khan missed international exposure for the next 3 years, as Pakistan was suspended from all football activities by FIFA on 10 October 2017. For three years since March 2015, Pakistan remained suspended from any international competition because of the crisis created inside the Pakistan Football Federation. In 2018, Khan participated in Pakistan tour to Bahrain for test matches as a preparation for the 2018 Asian Games and the 2018 SAFF Championship, when his national side returned to international circuit after 3 years. In the 2018 SAFF Championship, Pakistan terminated the campaign sealing its place in the semi-finals. He was also called for a two-match friendly series against Palestine the same year. In 2019, Khan played in the 2022 World Cup qualification against Cambodia, as Pakistan failed to qualify for the next round. This was before Pakistan were once again suspended from all…

International

As of match played 12 September 2019

Mehmood's brother Dawood Khan is also a footballer, and has played alongside him at KRL and K-Electric.