Thomas Van Den Keybus

Club Brugge

Van den Keybus made his professional debut with Club Brugge II in a 2–0 Belgian First Division B loss to RWDM47 on 22 August 2020. The following week, Club Brugge announced that they had extended Van den Keybus' contract through 2023. A month after his professional debut, on 27 September 2020, he also made his debut for the first team of Club Brugge in a league match against Cercle Brugge, where he came on as a substitute for Ruud Vormer four minutes before time. On 4 February 2022, Club announced that they had extended their contract with Van den Keybus for a second time, this time through 2025.

Westerlo

On 13 August 2021, Van den Keybus joined Westerlo on a season-long loan. Van den Keybus debuted for Westerlo on 15 August 2021, during a 2–0 victory over Virton. On 4 February 2022, the same day that Van den Keybus extended his contract with Club, it was announced that his loan at Westerlo would be extended through the 2022-23 season. On 5 July 2023, Van den Keybus returned to Westerlo on a permanent basis and signed a three-year contract.