Orlando Enrique Berrío

Born in Cartagena, Berrío played for Expreso Rojo and Atlético Nacional as a youth. He made his first team – and Categoría Primera A – debut on 22 February 2009, starting in a 0–1 home loss against Deportes Quindío. Berrío scored his first professional goal on 8 April 2010, in a 2–0 home win against América de Cali. Three days later, he netted a brace in an away success over Cortuluá, for the same scoreline. Sparingly used, Berrío was loaned to fellow top-tier club Millonarios on 3 January 2012. On 3 August 2012, after failing to score a single goal for the club, he was loaned to Patriotas for one year. Returning to Nacional, Berrío was regularly utilized by new manager Juan Carlos Osorio.

Flamengo

On 27 January 2017, Flamengo agreed to pay US$3.5 million to Atlético Nacional to sign Berrío. Berrío debuted for Flamengo in a Primeira Liga match against Grêmio on 8 February 2017, replacing Federico Mancuello in the 62nd minute and scoring his first goal for his new club in the 78th minute, while Flamengo won 2–0. On 22 October 2017, in a Brazilian Série A match against São Paulo at Pacaembu Stadium, Berrío suffered a knee injury that later was confirmed as an anterior cruciate ligament injury. In the same week, he underwent surgery, causing him to miss the rest of the 2017 season.

Khor Fakkan

On 19 July 2020, Berrío signed with Khor Fakkan.

América Mineiro

After spending an entire year without playing at Khor Fakkan, Berrío signed with América…

In August 2016, Berrío was named in Colombia's squad for 2018 FIFA World Cup qualifiers against Venezuela and Brazil. He did not play in either match, and only made his full international debut on 6 October, coming on as a substitute for Juan Cuadrado in a 1–0 away win against Paraguay.

Club

As of match played 21 September 2025.

International

As of 9 September 2019

Club

Atlético Nacional Categoría Primera A: 2011–I, 2013–II, 2014–I, 2015–II Copa Colombia: 2013, 2016 Superliga Colombiana: 2016 Copa Libertadores: 2016 Flamengo Campeonato Brasileiro Série A: 2019 Campeonato Carioca: 2017, 2019, 2020 Copa Libertadores: 2019 Supercopa do Brasil: 2020 Recopa Sudamericana: 2020